POLYSACCHARIDES USED IN OBTAINING HYDROGELS
FOR CONTROLLED DRUG DELIVERY SYSTEMS
This paper is a review of the most important papers related to
polisaccharides studied and used in hydrogels systems for controlled drug
delivery. Among the numerous macromolecules that can be used to obtain
hydrogels, polysaccharides present many advantages comparatively to
synthetic polymers being largely found in living organisms. Coming from
renewable sources, polysaccharides also have frequently economical
advantages over synthetic polymers, because they are non-toxic, biocompatible
and bioavailable, showing such physico-chemical proprieties that make them
suitable for applications in drug delivery systems. Focusing on the ability of
polysaccharides to form hydrogels in a great diversity of compositions it is well
understood that safer and more realistic approaches in the therapy of diseases
will be achieved in the days to come.
Key words: polysaccharides, hydrogels, controlled release drug
Cuvinte cheie: polizaharide, hidrogel, eliberarea controlată a medicamentelor